Adaptability key to success of cohort studies

first_img Read Full Story With federal research dollars declining, investigators must think of creative and flexible ways to keep their long-running cohort studies running and funded, said Bruce M. Psaty, professor of medicine and epidemiology at the University of Washington, at the 158th Cutter Lecture on Preventive Medicine at Harvard School of Public Health (HSPH) on December 5, 2013. Some of the ways he mentioned included being more willing to share data and seeking out new collaborations.Cohort studies follow and compare groups of people generally for years, tracking disease risk factors, health outcomes, and other factors (such as smoking habits or diet). Psaty, who has served as principal investigator of many large epidemiological studies, shared his recent experience successfully overcoming federal funding challenges as an investigator with the Cardiovascular Health Study.The long-running study, sponsored by the National Institutes of Health’s National Heart, Lung and Blood Institute, has tracked cardiovascular risk factors in people age 65 and over since 1988, producing 1,000 papers and 200 ancillary studies.“Adaptation is a way to keep the cohort alive, vital, and functioning,” Psaty said in his talk, “Cardiovascular Cohort Studies in Times of Big Data and Financial Austerity: The Cardiovascular Health Study as One Model.” Sharing data and collaborating with new investigators can help keep these studies thriving during challenging economic times, he said. “Take small steps and be crafty along the way.”last_img read more

Mission-Critical Meets All-Flash

first_imgIT organizations are modernizing their data centers at an accelerated rate. The newly engineered VMAX All Flash storage family that we announced today combines the trusted data services and enterprise scale of VMAX with the performance and density of high-capacity flash drives. The result is a proven platform capable of delivering new levels of scale and performance to help modernize IT more quickly and with lessrisk.It has been an extremely exciting time for the VMAX team as we worked to get this product available for our users’ data centers. There has been a buzz in the air, not just because engineers like to work on cool technology and innovation, but because the entire team is jazzed and confident they have built a platform for our users that can help transform their IT infrastructures and radically improve the way they manage and support their most-critical applications.So why VMAX All Flash? It’s because we truly believe that the combination of all- flash technology with the enterprise capabilities of VMAX is a critical success factor for the modern data center. Almost every CIO we meet who is responsible for large-scale enterprise environments has a common set of criteria for systems that support their critical applications. These include:Supporting an extensive ecosystem to provide a common, standardized way of delivering storage services for a range of platform, OS, hypervisor, and application types.Delivering management, automation, and simplicity at enterprise scale to abstract the underlying technology to eliminate manual administration and lower operational costs.Providing massive consolidation and efficiencies with flash technology to enable predictability, scale, and control for service provider and large enterprise requirements.Enable rock-solid replication and integrated backup data services to protect mission-critical apps, maintain “always on” data availability, and avoid disasters.VMAX All Flash meets this checklist in a way that no other product in the industry can. Building on customer expectations of VMAX as the most trusted array on the planet, VMAX All Flash is a major leap forward in delivering the capabilities of the modern data center.We are proud of the team and the innovation they have put into this platform. We are also thankful to our users who have placed their trust in VMAX to manage some of the world’s most-critical apps, a responsibility everyone on the team thinks about every day. And we are excited for the future, as we aim to deliver even more innovation and greater business value, without compromising the reasons why VMAX remains at the heart of the modern data center.last_img read more

Suspect in 1972 Murder Dies in Apparent Suicide Hours Before Conviction

first_imgA man who eluded homicide investigators in Washington State for nearly 50 years — until a DNA match on a coffee cup cracked the cold case — died in an apparent suicide on Monday just hours before a jury convicted him of murder, the authorities said. The man, Terrence Miller, 78, was charged last year with killing Jody Loomis in 1972 in Snohomish County, which is about 20 miles north of Seattle. – Advertisement – Just before 10 a.m. on Monday, sheriff’s deputies in Edmonds, Wash., responded to a report of a suicide and found what they believed to be Mr. Miller’s body, the Snohomish County Sheriff’s Office said. Mr. Miller had been out on bond, and a family member reported the suicide, the sheriff’s office said. About three hours later, in Snohomish County Superior Court, a jury that had been hearing the case against Mr. Miller for two weeks convicted him of the murder of Ms. Loomis. The judge in the case announced in court that Mr. Miller had died, a local radio station reported. A final determination on Mr. Miller’s cause of death won’t be made until at least Tuesday, a spokeswoman for the county medical examiner wrote in an email on Monday night. When two undercover detectives visited a ceramics business that Mr. Miller ran with his wife out of their garage in November 2018, they noticed a nearly seven-month-old newspaper on a table with a headline about an arrest made in another cold case in Snohomish County, the affidavit said. That case involved the double murder of a young couple from British Columbia in 1987, which led to the conviction of William Talbot II.“The presence of the newspaper seemed, at best, an odd coincidence,” the affidavit said. “A fair inference could also be drawn that the defendant was keeping track of the techniques that law enforcement was using to solve cold cases.” Genetic genealogy has been instrumental in identifying more than 40 suspects in languishing cold cases, most notably the so-called Golden State Killer in California. It also led to a double-murder conviction in another high-profile case in the same Pacific Northwest county where Ms. Loomis was killed. – Advertisement – Ms. Loomis, 20, had been riding her bike to visit her horse at a nearby stable when she was sexually assaulted and then shot in the head with a .22-caliber gun, according to a probable cause affidavit.Investigators used genetic genealogy, a process that involved crosschecking DNA evidence — taken from a hiking boot worn by Ms. Loomis — with ancestry records to connect Mr. Miller to the unsolved murder. They did not know each other, the authorities said. center_img – Advertisement – – Advertisement – Terrance Miller in a photograph believed to have been taken around the time Ms. Loomis was murdered.Credit…Snohomish County Sheriff’s Office For decades, the killing of Ms. Loomis had stumped investigators. A couple who had gone out target shooting discovered her partially nude body off a secluded dirt road near Bothell, Wash, on Aug. 23, 1972. Semen was recovered from Ms. Loomis’s body and from a “waffle stomper” hiking boot that she had been wearing at the time and had borrowed from her sister. In 2008, the samples were sent to the Washington State Patrol Crime Laboratory for DNA testing, but they did not return a match. The breakthrough in the case came in 2018 when investigators, working with Parabon NanoLabs, were able to put together a family tree of possible suspects based on the semen sample found on the heel of the victim’s hiking boot. The company uses DNA to help law enforcement agencies find genetic matches.That’s when investigators began their surveillance of Mr. Miller, whom they followed to a nearby casino and from whom they retrieved a coffee cup that he had thrown in the garbage, the probable cause affidavit said. The DNA sample was an exact match to the semen found on Ms. Loomis’s boot, the affidavit said. He was arrested in April 2019 and charged with first-degree murder.Both of Ms. Loomis’s parents are deceased, and her sister could not be immediately reached for comment on Monday night. Laura Martin, the public defender for Mr. Miller, contested the integrity of the DNA evidence in an email to The New York Times on Monday night.“Death seemed preferable to letting a jury decide a verdict on tainted evidence,” Ms. Martin wrote. “This is a terrible tragedy that began with Jody Loomis’s death and is compounded by an innocent man taking his own life.”last_img read more

Mexico says 1,200 citizens died in US from coronavirus

first_imgRemittances sent home from Mexicans living abroad is an important source of income for many people.Those coming from the US dropped 2.6 percent in April compared to the same month in 2019, having reached a record of more than $4 billion in March 2020.Some 12 million people born in Mexico live in the US, as well as another 26 million second or third generation Mexicans.Mexico, a country of 127 million, had recorded more than 120,000 coronavirus cases by Monday and over 14,000 deaths, making it one of the worst hit countries in Latin America. Topics : More 1,200 Mexicans have died of the novel coronavirus in the United States, Mexico’s Foreign Minister Marcelo Ebrard said on Tuesday, adding that another 12 citizens around the world have also fallen victim to the deadly virus.Ebrard said more than half of the US deaths were in New York, while five of the worldwide deaths happened in Canada.As borders all over the world were closed due to the pandemic, Mexico repatriated more than 14,600 people, including almost 4,000 from Europe, Ebrard said.last_img read more

Low-Interest Loan Financing Provided by Wolf Administration in 2018 Will Support More Than 4,300 Jobs

first_imgLow-Interest Loan Financing Provided by Wolf Administration in 2018 Will Support More Than 4,300 Jobs Economy,  Jobs That Pay,  Press Release Harrisburg, PA – Governor Tom Wolf announced that in 2018, the Pennsylvania Industrial Development Authority (PIDA) has approved more than $84 million in loan financing throughout the year. This financing will support the creation and retention of more than 4,300 jobs in the commonwealth.“Providing access to capital is one of the best ways we can help businesses of all sizes grow and expand,” Governor Wolf said. “The loans approved in 2018 through PIDA are helping lay the groundwork for these businesses to create jobs and positively impact their local economies for years to come.”In 2018, PIDA has approved $84,034,418 in low-interest loans that have resulted in $119,561,991 in private investment and supported the creation and retention of 4,316 full-time jobs. PIDA is an independent authority staffed and regulated through the Department of Community and Economic Development (DCED). The authority provides capital for building acquisition, construction and renovation work, machinery, and equipment loans along with working capital lines of credit, primarily for manufacturers, industrial developers, research and development firms, agricultural processors, and employers looking to establish national or regional headquarters in Pennsylvania.One such loan recipient is Creekside Springs in Beaver County, which provides high-quality water to beverage companies, supermarkets, large retailers, and businesses located in Pennsylvania and Ohio. In June 2018, Governor Wolf announced that Creekside Springs was approved for a $400,000 loan to upgrade its bottling and production line in its New Brighton facility.“The PIDA loan advanced our timeline to install the production line and transform our New Brighton facility from a warehouse into a functional bottling facility faster than anticipated,” said James Sas, managing partner of Creekside Springs. “Pennsylvania felt like the right place for Creekside Springs to grow and operating here has exceeded our expectations.”At today’s PIDA board meeting, High Functional Plastics Manufacturing, LLC was approved for a $350,000, 10-year loan at a 3.75 percent rate through the Northeastern Pennsylvania Alliance. The loan will be used for the purchase of machinery and equipment to be installed and utilized at the company’s 12,000-square-foot manufacturing facility in Dunmore, Lackawanna County. High Functional Plastics Manufacturing is a startup manufacturer of corrosion-resistant extruded plastic sheets used in the construction of semiconductor processing equipment and similar electronic products.For more information about the Pennsylvania Industrial Development Authority and other DCED initiatives, visit SHARE Email Facebook Twittercenter_img January 09, 2019last_img read more

Somalia marks 55 Years of Independence

first_imgIt is a nation that has witnessed the harshest consequences of internal conflict. Somalia has endured a torrid existence, with no formal government for more than two decades, as well as a continuing drawn out war against militant group Al Shabaab. But such major challenges are not stopping Somalis from celebrating fifty five years of independence Related Kenya celebrates 50 years of independence Somalia marks a year without Polio Somalia reopens US embassy after 25 yearslast_img

Cuba proving attractive to Canadian banks

first_imgLifestyleMoney Cuba proving attractive to Canadian banks by: – December 22, 2011 Scotiabank and RBC reportedly eyeing Cuba as a new Caribbean investment opportunity.HAVANA, Cuba, Thursday December 22, 2011 – As Cuba’s march toward private sector reform continues, its new business environment is proving increasingly attracting to foreign investment. According to reports coming out of Canada, the Bank of Nova Scotia has reportedly applied to Cuban authorities to set up a representative office in the capital while Royal Bank is also considering opening an office in Havana.Both banks already have extensive operations across South America and the Caribbean.While the Montreal-based National Bank of Canada has operated an office in Cuba for 16 years, this potential move by two of Canada’s largest banks could be seen as legitimising the Raul Castro-led economic reforms that have been taking place on the island.Just this week the Cuban government announced that banks on the island can now offer loans to private entities and individuals in order to accelerate the burgeoning entrepreneurial class. The state newspaper Granma said about 500 banks in Cuba will offer the loans, although it remains unclear what interest rates they will charge. Applicants will find out if their loans are approved within twenty days, the paper indicated.Reportedly, self-employed Cubans will receive minimum loans of about US$125, while farmers will receive at least US$40.In addition, Cubans will also be able to avail themselves of debit cards, checks, and bank transfers – that is, services common to citizens of capitalist nations.This liberalisation in banking could signal to the two large Canadian banks that it might be worth re-entering the waters in the Spanish-speaking nation. Scotiabank and RBC both had branches in the country before the 1959 Cuban Revolution ushered in Communism, and a subsequent U.S. embargo, which slowed foreign investment.National, Canada’s sixth-largest bank, opened a representative office in Havana in 1995. The small operation is not a bank branch though, and mostly handles trade finance.Banco Central de Cuba, the country’s central bank, lists National as having a relationship with the country that dates back more than 28 years, including financing export development, securities and insurance businesses there.The Cuba Trade and Economic Council lists more than 80 companies in Canada with business ties to Cuba, including Bell Canada, Bombardier, and dozens of oil and gas companies. Caribbean 360 News Tweet Share 167 Views   no discussionscenter_img Share Sharing is caring! Sharelast_img read more

Villar still richest senator, Bong Go among poorest

first_imgJoining her inthe billionaire’s club is boxing champ-turned-Senator Manny Pacquiao with a networth of P3 billion. * Sen. PiaCayetano – P82,308,227.36 (As of July 1, 2019) Her wealth, however, dipped by over P185 million compared to last year’s net worth of P3.72 billion. * Sen. GracePoe – P95,693,450.37 (As of June 30, 2019) Pacquiao, who has amassed a huge fortune from his lengthy boxing career, recorded the highest liabilities at P146 million as of Dec. 31, 2018.  * Sen. Ronald“Bato” Dela Rosa – P28,258,908 (As of June 30, 2019) * Sen. MannyPacquiao – P3,005,808,000 (As of Dec. 31, 2018) * Sen. JuanEdgardo “Sonny” Angara – P139,026,597 (As of June 30, 2019) * Sen.Christopher Lawrence “Bong” Go – P15,508,370.82 (As of June 30, 2019) * Sen. Leila deLima – P7,706,392.45 (As of December 31, 2018)(ABS-CBN News/PN) * Sen. NancyBinay – P59,911,019 (As of June 30, 2019) Senators areunder salary grade 31, which is equivalent to monthly pay of at least P117,086,according to the Department of Budget and Management. * Sen. Panfilo“Ping” Lacson – P42,442,341 (As of Dec. 31, 2018) The thirdrichest member in the Senate is Sen. Ralph Recto with a net worth of P555million, followed by Sen. Juan Miguel Zubiri with a net worth of P182 millionand reelected Sen. Ramon Bong Revilla Jr. with a net worth of P164 million. * Sen. JoelVillanueva – P26,921,555 (As of Dec. 31, 2018) * Sen. KokoPimentel – P29,934,635 (As of June 30, 2019) * Sen. RamonBong Revilla Jr. – P164,203,379.38 (As of June 30, 2019) * Sen. Richard“Dick” Gordon – P71,285,178.56 (As of December 31, 2018) * Sen. FrancisTolentino – P62,482,000 (As of June 30, 2019)center_img * Sen. JuanMiguel Zubiri – P182,851,570.34 (As of Dec. 31, 2018) Go, who is President Rodrigo Duterte’s former special assistant, spent some P161 million in his Senate bid during the 2019 midterm elections.  MANILA – Sen.Cynthia Villar remains the richest member of the Senate in 2019, based onsenators’ latest statements of assets, liabilities and net worth (SALNs). Meanwhile,ranking at the bottom of the 24-seat chamber are Senators Leila de Lima withP7.7 million, Christopher Lawrence “Bong” Go with P15.5 million, RisaHontiveros with P15.6 million, Francis “Kiko” Pangilinan with P16.7million and Joel Villanueva with P26.9 million. * Sen. FranklinDrilon – P97,726,758 (As of Dec. 31, 2018) * Sen. RalphRecto – P555,324,479.82 (As of Dec. 31, 2018) * Sen. RisaHontiveros – P15,627,176.04 (As of Dec. 31, 2018) * Sen. SherwinGatchalian – P96,210,607.14 (As of Dec. 31, 2018) Below is the complete ranking of the senators based on their latest declared net worth. * Sen. Vicente“Tito” Sotto III – P70,120,700.30 (As of Dec. 31, 2018) * Sen. Manuel“Lito” Lapid – P69,910,000 (As of June 30, 2019) Rounding up thetop 10 of wealthiest senators are Juan Edgardo “Sonny” Angara withP139 million; Franklin Drilon with P97 million; Sherwin Gatchalian with P96million; Grace Poe with P95 million; and Pia Cayetano with P82 million. * Sen. Francis“Kiko” Pangilinan – P16,695,048.17 (As of Dec. 31, 2018) * Sen. ImeeMarcos – P29,970,467 (As of June 30, 2019) * Sen. CynthiaVillar – P3,534,412,797 (As of June 30, 2019) Villar, whosefamily has interest in property and shopping malls, posted a net worth of P3.53billion with no liabilities as of June 30, 2019.  He was the topcampaign spender among winning bets, followed by Tolentino with P159 million,Poe with P156 million, Angara with P153 million, Villar with P135 million,Marcos with P132 million and Revilla with P121 million.last_img read more

Manchester City boss Manuel Pellegrini: No news on Kevin de Bruyne

first_img Pellegrini said: “I think playing with creative players such as Kun (Sergio Aguero), (Samir) Nasri, (David) Silva, Yaya (Toure) – sorry not to tell aloud another player, just the players that we have – I think he will improve a lot, scoring more goals. “The good thing of Sterling is that he is not just about scoring goals, he works a lot during the whole game. There are a lot of reasons why we got him and he is demonstrating that he is not (just) an expensive player, but a good player.” City have made a flying start to the season, winning their first four games without conceding a goal. In all they have now won a club record 10 in succession and they are already eight points ahead of chief title rivals and champions Chelsea. Pellegrini said: “I think we played this game in exactly the same way we played the other three games, as a very consistent team. “We had different rivals in the four games but we found the solutions, especially today when we didn’t create many chances because Watford defended very well. In that sense I am very happy about that.” Defeat was Watford’s first of the season after three successive draws. Manager Quique Sanchez Flores admitted holding City out was always likely to prove difficult for his side. He said: “I think we played well in the first half in defensive terms but it was difficult to resist City for the full match. It was very difficult to play against this kind of opponent. “They have a lot of velocity in the transition, they have a lot of quality in the pass, they are physically strong. “For the future we will learn from this kind of experience. It is very difficult to play against City in these conditions.” Press Association Manchester City manager Manuel Pellegrini has continued to rebuff questions about Kevin de Bruyne. Pellegrini faced a series of queries about the Belgian, the subject of a reported £58million offer from City, after his side’s 2-0 win over Watford on Saturday. Earlier in the day it was reported the Wolfsburg playmaker was in Manchester for a medical but, in keeping with a stance of indifference adopted throughout City’s lengthy apparent pursuit, Pellegrini remained non-committal. “I don’t have any news,” Pellegrini said at his post-match press conference at the Etihad Stadium. “You have news? “I will answer the same way I answer all the questions that you or the other journalists ask me about rumours. I can’t talk about rumours.” It was then suggested that the reports could no longer be considered rumours because Wolfsburg have commented and a photograph of De Bruyne apparently in Manchester has also emerged. But, in an odd exchange, Pellegrini said: “He has signed? It is the first thing I know… He has not signed. I answer what I want and not what you want. I cannot talk about things they never told me, that he has signed a contract.” It was then suggested that Pellegrini might at least know that De Bruyne was in Manchester, but again he refused to answer. He said: “I was involved in the game and not thinking about what was happening in Manchester. I was thinking about what happened in 90 minutes against Watford.” There was, however, a slight hint that another signing might be imminent as he discussed the goalscoring performance of Raheem Sterling who, for the moment at least, remains City’s record signing at £49million. Sterling scored his first goal for City in the second minute of the second half and Fernandinho doubled the lead as the Barclays Premier League leaders finally broke the resistance of the spirited Hornets. last_img read more

Titans president lauds parents, players for initiative shown during covid19 lockdown

first_img-Says measures in place to protect players, fans in the futureBy Clifton RossPRESIDENT of the Titans Table Tennis Club Dwayne Dick, lauded the actions taken by both players and parents following the current state of lockdown on sports.Table-Tennis players like many others have been served some indefinite downtime due to the covid-19 spread which continues to wreak havoc globally.Speaking with Chronicle Sports yesterday, Dick said he was overwhelmed by the support and efforts shown by the parents of the young table tennis players.“I have to commend the player’s parents. Some of the parents have really stepped up to ensure that the players stay fit, by watching videos on techniques and other training methods. I also have been sharing some as well and I have been advising parents to some extent as to the relevant workouts” Dick outlined.One of the highlights of the quarantine according to the president is the dedication shown by Colin Wong, the 2019 bronze medallist In Boys Under 13 at CRTTF championship, boys singles and doubles.Wong has been hitting the weights daily while working on his technique and according to his coach, “He’s very motivated and staying disciplined throughout all this”.Colin Wong doing some weight trainingHe added that it is crucial for all the athletes to maintain their fitness. “For them it’s more about long term development, a way of life for them. This is the opportune time for them to go hard in terms of strength and conditioning because they have more time to rest and recover”.He continued, “I also encourage them to catch up with schoolwork, bcus that is always a challenge for student athletes, who usually juggle the two. As a matter of fact I am tutoring some of them in math via virtual platforms”.Speaking on the energy coming from the camp, Dick said the feedback was positive from his players. “They are learning to cope with uncertainty and learning to appreciate the fact that they are capable of adjusting to circumstances. ”Most importantly, whenever sports locally resumes, safety will be key and the club head echoed similar sentiments, saying measures are already in place to ensure player’s safety is optimum.“Less players at training sessions,” Cleaning the ball, racket and tables frequently. Also fumigating the venue regularly. We will be monitoring or testing maybe once a month for Covid until such time”. He confirmed.With regards to fans, plans are also in place to ensure they too are kept safe. “We will have to limit spectators at tournament venues and play less categories a day to minimise player contact”. Dick ended.last_img read more